High viscosity composition
AssigneeBecare Orthopedic Thermal Care AB
InventorsChrister Höglund, Dag Kryzaniak
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Abstract
A high viscosity composition which according to the invention comprises at least one polyoxyethylene-polyoxypropylene-block copolymer (poloxamer) having the structural formula HO(C2H4O)a (C3H6O)b (C2H4O)a H and having an average molecular weight of above 6000; at least one additional polymer having an average molecular weight of above 150000, and a dispersion medium, comprising at least one freezing point depressing dispersant and at least one freezing point non-depressing dispersant. The composition is heatable above the body temperature of a mammal and coolable below 0° C. within a predetermined temperature range.
Claims9
A high viscosity composition for application onto extremities of a mammal, which is heatable above a body temperature of the mammal and coolable below 0° C. within a predetermined termperature interval and which comprises:
- a polyoxyethylene-polyoxypropylene-block copolymer having the structural formula
- HO(C2H4O)a (C3H6O)b (C2H4O)a H;
- an additional polymer;
- and
- a dispersion medium, comprising at least one freezing point depressing dispersant and at least one freezing point non-depressing dispersant;
- wherein said polyoxyethylene-polvoxypropylene-block copolymer is poloxamer 407 having an average molecular weight of about 12600 and wherein a is 101 and b is 56,
- said poloxamer 407 being included in an amount of 10-25% by weight of the composition,
- said additional polymer is polyvinylpyrrolidone having an average molecular weight of about 1 million and being included in an amount of 5-20% by weight of the composition,
- said freezing point depressing dispersant is selected from the group consisting of propylene glycol, ethylene glycol, butylene glycol and glycerol,
- said freezing point non-depressing dispersant is selected from the group consisting of water and a higher alcohol having a boiling point above 100° C. and mixtures thereof, and
- said freezing point depressing dispersant constitutes 20-90% of the dispersion medium and the freezing point non-depressing dispersant constitutes 80-10% of the dispersion medium, and
- wherein the composition also comprises a strong electrolyte selected from the group consisting of sodium, potassium, calcium and magnesium chloride, said electrolyte being included in an amount of 2-7% by weight of the composition.
Dependencies are inferred from the claim text.