Tissue patches and related delivery systems and methods

A tissue patch for treatment of a lesion in an alimentary tract of a patient, comprising:

• a substrate having a first surface and a second surface opposite the first surface;
• an implant of tissue attached to the first surface of the substrate and occupying a first area of the first surface;
• a protective liner removably attached to the first surface of the substrate so that the implant of tissue is placed between the substrate and the protective liner and so that the protective liner contacts and covers the implant of tissue;
• and
• an adhesive material for attaching the protective liner to the substrate,
• wherein the adhesive material occupies a second area of the first surface that is different from the first area, wherein the second area comprises an outer edge of the first surface, and wherein each of the implant of tissue and the adhesive material is disposed between the substrate and the protective liner.

A tissue patch for treatment of a lesion in an alimentary tract of a patient, comprising:

• a substrate having a first surface and a second surface opposite to the first surface,
• wherein the substrate is a bio-absorbable gel;
• a sheet of tissue attached to the first surface of the substrate, the sheet of tissue occupying an area of the first surface, the area being less than the surface area of the first surface;
• and
• a protective liner removably attached to at least one of the substrate and the sheet of tissue to cover the sheet of tissue,
• wherein the sheet of tissue is disposed between the substrate and the protective liner.

A tissue patch for treatment of a lesion in an alimentary tract of a patient, comprising:

• a substrate having a first surface and a second surface opposite the first surface,
• wherein the substrate is a bio-absorbable gel;
• an implant of tissue attached to the first surface of the substrate and occupying a first area of the first surface;
• a protective liner attached to the first surface of the substrate so that the implant of tissue is placed between the substrate and the protective liner;
• and
• an adhesive material for attaching the protective liner to the substrate,
• wherein the adhesive material occupies a second area of the first surface that is different from the first area, wherein the second area comprises an outer edge of the first surface, and wherein each of the implant of tissue and the adhesive material is disposed between the substrate and the protective liner.