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US 8,136,676 B2Granted
Polymers useful as medical materials
AssigneeUniversity of Southampton
InventorsHitoshi Mizomoto, Mark Bradley
Life of this patent
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Abstract
One object of the present invention is to provide polymers suitable for use as medical materials. The present invention provides a polymer useful as a medical material having the general formula -(A)1-(B)m—(C)n— (I) in which A is derived from an alkoxyalkyl (alkyl)acrylate monomer; B is derived from a monomer containing a primary, secondary, tertiary or quaternary amine group; C is derived from a non-ionic monomer; and 1+m+n=100,0<1, m, n<100.
Claims17
A separation system configured to remove a leukocyte from a liquid medium;
- the system comprising:
- a container defining an inlet, an outlet, and a volume of space;
- a separation medium occupying at least a portion of the volume of space;
- the container being configured for contacting the separation medium with the liquid medium;
- the separation medium comprising a surface portion;
- the surface portion comprising a ternary polymer of the general formula:
- -(D)o-(E)p-(F)q— (II)
- in which
- in which
- R1 is H or a lower alkyl group;
- R3, R10 are independently lower alkyl, phenyl or substituted phenyl groups;
- R4, R6, R7, R8, R11, R13, R15, R16 are independently H, lower alkyl, phenyl or substituted phenyl groups;
- R2, R5, R9, R14 are independently selected from CH2—CH2, CH2—CHRa, CHRa—CH2, CHRa—CHRb, CHRa—CRbRc, CRaRb—CHRc, CRaRb—CRcRd or (CH2)e, where e=2-6, and Ra, Rb, Rc, Rd are lower alkyl groups and Ra, Rb, Rc and Rd may be the same or different;
- R12 is H, a lower alkyl, phenyl, substituted phenyl or 1,1-dimethyl-3-oxobutyl group;
- X is O or NRf, where Rf is H or a lower alkyl group;
- s is 0 or s≧2;
- and
- o+p+q=100, 0<o, p, q<100.
15 more elements
A ternary polymer of general formula (II):
- -(D)o-(E)p-(F)q— (II)
- in which
- in which
- R1 is H or a lower alkyl group;
- R3, R10 are independently lower alkyl, phenyl or substituted phenyl groups;
- R4, R6, R7, R8, R11, R13, R15, R16 are independently H, lower alkyl, phenyl or substituted phenyl groups;
- R2, R5, R9, R14 are independently selected from CH2—CH2, CH2—CHRa, CHRa—CH2, CHRa—CHRb, CHRa—CRbRc, CRaRb—CHRc, CRaRb—CRcRd or (CH2)e, where e=2-6,and Ra, Rb, Rc, Rd are lower alkyl groups and Ra, Rb, Rc and Rd may be the same or different;
- R12 is H, a lower alkyl, phenyl, substituted phenyl or 1,1-dimethyl-3-oxobutyl group;
- X is O or NRf, where Rf is H or a lower alkyl group;
- s is 0 or s≧2;
- and
- o+p+q=100, 0<o, p, q<100.
9 more elements
Dependencies are inferred from the claim text.