Computer systems and methods for providing health care

A computer program product for use in conjunction with a computer system, the computer program product comprising a computer readable storage medium and a computer program mechanism embedded therein, the computer program mechanism comprising:

• one or more data structures associated with each patient in a plurality of patients enrolled in a health care program, the one or more data structures associated with each respective patient in the plurality of patients collectively comprising:
• a patient identifier for the respective patient;
• a molecular profile from one or more biological specimen obtained from the respective patient where the molecular profile comprises a longitudinal molecular profile for the patient, the longitudinal molecular profile being developed over time and being updated in response to one or more treatment regimens that have been provided to the respective patient;
• a current clinical characterization of the respective patient including an updated clinical assessment based on treatment of the respective patient by the one or more treatment regimens;
• and
• a plurality of treatment regimens and evidence based data relating to an outcome of treating one or more of the plurality of patients with one of the plurality of treatment regimens, wherein one or more of the plurality of treatment regimens is updated based at least in part on assessments of patients after treatment in accordance with a given treatment regimen;
• and
• a therapeutic determination module comprising:
• instructions executable by one or more processors for identifying a treatment regimen, from among the plurality of treatment regimens, for a patient in the plurality of patients based at least in part on the molecular profile, the current clinical characterization and the evidence based data.