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US 8,134,032 B2Granted
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
AssigneeGruenenthal GmbH
InventorMichael Gruss
Life of this patent
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Abstract
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol, pharmaceutical compositions which contain these modifications, and the use thereof to treat pain or other conditions.
Claims27
A crystalline modification of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol selected from the group consisting of:
- crystalline modification A having X-ray diffraction peaks at 14.80±0.20 (2Θ), 15.58±0.20 (2Θ), 17.79±0.20 (2Θ) and 25.33±0.20 (2Θ);
- crystalline modification B having X-ray diffraction peaks at 14.11±0.20 (2Θ), 16.08±0.20 (2Θ), 17.17±0.20 (2Θ) and 29.06±0.20 (2Θ);
- and
- crystalline modification C having X-ray diffraction peaks at 10.93±0.20 (2Θ), 16.43±0.20 (2Θ), 21.17±0.20 (2Θ) and 24.92±0.20 (2Θ).
1 more element
Dependencies are inferred from the claim text.