Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine
AssigneeSunovion Pharmaceuticals Inc.
InventorsThomas Jerussi, Qun Kevin Fang, Mark G. Currie
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Abstract
Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
Claims18
A method for treating cerebral function disorders involving intellectual deficits, the method comprising administering to a person in need of treatment for cerebral function disorders involving intellectual deficits a therapeutically effective amount of a compound of formula PQ:
- or a salt thereof
A method for treating cerebral function disorders associated with schizophrenia, the method comprising administering to a person in need of treatment for cerebral function disorders associated with schizophrenia a therapeutically effective amount of a compound of formula PQ:
- or a salt thereof.
A method for treating intellectual deficits associated with schizophrenia, the method comprising administering to a person in need of treatment for intellectual deficits associated with schizophrenia a therapeutically effective amount of a compound of formula PQ:
- or a salt thereof.
Dependencies are inferred from the claim text.