Method of fabricating mesocrystals of organic and organo-metallic compounds

A method of fabricating mesocrystals of racemic (R,S)-(±)-sodium ibuprofen dihydrate, comprising the steps of:

• (a) obtaining a mixture of racemic (R,S)-(±)-sodium ibuprofen dihydrate and a surfactant;
• (b) obtaining a supersaturated solution with said racemic (R,S)-(±)-sodium ibuprofen dihydrate and said surfactant, placing said supersaturated solution in a glass vial having a cross-shaped magnetic spin bar, and placing said glass vial in a crystallizer;
• and
• (c) obtaining a mesocrystal through a water bath with a crystallizer having three constant temperature tanks, comprising the steps of:
• (c1) processing a stirring in said glass bottle located in a first constant temperature tank of said crystallizer;
• (c2) placing said glass bottle in a second constant temperature tank of said crystallizer and processing a stirring to completely dissolve said organic or organo-metallic compound, wherein said second constant temperature tank has a higher temperature than said first constant temperature tank;
• (c3) placing said glass vial back to said first constant temperature tank and staying said glass vial still for a period of time;
• (c4) rapidly moving said glass vial to a third constant temperature tank of said crystallizer to obtain a mesocrystal in said glass bottle, wherein said third constant temperature tank has a lower temperature than said first constant temperature tank.