Substituted N-bicyclicalkyl bicycliccarboxyamide compounds

A compound of the formula (I):

• wherein ring A is
• wherein
• one of X1 and X3 is N, another of X1 and X3 is NH or S, and X2 is N or CR5,
• one of X1 and X3 is CH2, another of X1 and X3 is NH or N, and X2 is C═O or N,
• one of X1 and X3 is CR6, another of X1 and X3 is NH, and X2 is N or CR5,
• X1 and X3 are NH and X2 is C═O, or
• Y1 is N or CR7, Y2 is N or CR8, Y3 is N or CR9 and Y4 is N or CR10;
• the substitution site of ring B is the alpha- or beta-position;
• E is CH or N;
• G, J and K are each CH;
• F is CH or C—CH3;
• L is N and T is CH;
• R1 and R2 are each independently hydrogen, (C1-C6)alkyl, or hydroxy(C1-C6)alkyl;
• R3 is hydrogen;
• R4 is (C1-C6)alkyl, hydroxy(C1-C6)alkyl, (C3-C6)cycloalkyl, (C1-C4)alkyl(C3-C6)cycloalkyl, (C1-C4)alkoxy(C1-C6)alkyl optionally substituted with halo or halo(C2-C6)alkyl optionally substituted with hydroxy, R5 and R6 are each independently hydrogen, (C1-C6)alkyl, hydroxy(C1-C6)alkyl or hydroxy(C1-C6)alkoxy-(C1-C6)alkyl;
• R7, R8, R9 and R10 are each independently hydrogen, halo, (C1-C6)alkyl, hydroxy(C1-C6)alkyl or hydroxy(C1-C6)alkoxy-(C1-C6)alkyl;
• and each dotted bond is a single or a double bond;
• or a pharmaceutically acceptable salt thereof.