Back to results
US 8,134,002 B2Granted
Process for preparing oxymorphone
AssigneePenick Corporation
InventorBao-Shan Huang
Life of this patent
Estimating the term…
Abstract
Methods are provided which include converting oripavine to other opiates, including converting oripavine to 14-hydroxymorphinone and/or converting 14-hydroxymorphinone to oxymorphone. Purification and salt formation are optionally included.
Claims11
A method of preparing oxymorphone or a salt thereof comprising:
- oxidizing oripavine to obtain 14-hydroxymorphinone, wherein said oxidizing is performed in a single step with an oxidizing agent comprising performic acid, peracetic acid or m-chloroperoxybenzoic acid in a solvent comprising formic acid or acetic acid;
- and
- reducing the 14-hydroxymorphinone to obtain oxymorphone.
Dependencies are inferred from the claim text.