Dipeptides for prevention of muscle breakdown and microbial infection
AssigneeUniversity of Florida Research Foundation, Inc.
InventorJosef Neu
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Abstract
The subject invention provides dipeptides useful in promoting healthy muscle tissues as well as effective immune responses. The dipeptides of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.
Claims11
An aqueous, enteral nutrient formulation comprising an arginyl-glutamine dipeptide and at least one additive, wherein the arginine residue is the amino terminus of said dipeptide and the glutamine residue is the carboxy terminus of said dipeptide, and wherein the additive is selected from the group consisting of vitamins, minerals, trace elements, fats, monosaccharides and oligosaccharides.
A method for increasing healthy muscle tissue in a human or animal, said method comprising administering to a human or animal in need of such treatment an effective amount of an aqueous enteral nutritient formulation comprising an arginyl-glutamine dipeptide and at least one additive, wherein the arginine residue is the amino terminus of said dipeptide and the glutamine residue is the carboxy terminus of said dipeptide, and wherein the additive is selected from the group consisting of vitamins, minerals, trace elements, fats, monosaccharides and oligosaccharides.
A method for increasing immunity to pathogens in a human or animal, said method comprising administering to a human or animal in need of such treatment an effective amount of an aqueous, enteral nutrient formulation comprising an arginyl-glutamine dipeptide and at least one additive, wherein the arginine residue is the amino terminus of said dipeptide and the glutamine residue is the carboxy terminus of said dipeptide, and wherein the additive is selected from the group consisting of vitamins, minerals, trace elements, fats, monosaccharides and oligosaccharides.
Dependencies are inferred from the claim text.