Cell culture compartment unit and array including the same
AssigneeElectronics and Telecommunications Research Institute
InventorsSanghee Kim, Chul Am Kim, Chang-Geun Ahn, Moon Youn Jung
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Abstract
Provided are a cell culture compartment unit and an array including the same. The cell culture compartment unit includes: a cell culture region and a bio material emission region including a cell culture fluid, which are separated with a porous membrane therebetween; a piezoelectric device on the porous membrane of the cell culture region; a thin layer for cell attachment being on the piezoelectric device and having at least one surface on which cells are attachable; and a first power supply applying a first electric field to the piezoelectric device.
Claims17
A cell culture compartment unit comprising:
- a cell culture region, and a biomaterial emission region including a cell culture fluid, which are separated with a porous membrane therebetween;
- a piezoelectric device disposed over the porous membrane of the cell culture region;
- a thin cell attachment layer disposed over the piezoelectric device and comprising at least one surface to which cells are attachable;
- a first power supply configured to apply a first electric field to the piezoelectric device;
- a conducting electrode spaced apart from the porous membrane in a vertical direction and disposed within the biomaterial emission region;
- a conducting polymer including a biomaterial disposed between the conducting electrode and the membrane;
- and
- a second power supply configured to apply a second electric field to the conducting electrode in order to emit the biomaterial into the cell culture fluid.
A cell culture compartment array comprising a plurality of arranged cell culture compartment units, each of the cell culture compartment units comprising:
- a cell culture region and a biomaterial emission region including a cell culture fluid, which are separated with a porous membrane therebetween;
- a piezoelectric device disposed over the porous membrane of the cell culture region;
- a thin layer disposed over the piezoelectric device and comprising at least one surface on which cells are attachable;
- a first power supply configured to apply a first electric field to the piezoelectric device;
- a conducting electrode spaced apart from the porous membrane in a vertical direction and disposed within the biomaterial emission region;
- a conducting polymer disposed at an end portion of the conducting electrode close to the membrane;
- and
- a second power supply configured to apply a second electric field to the conducting electrode.
Dependencies are inferred from the claim text.