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US 8,133,687 B2Granted
Labor biomarkers, methods comprising same, and methods targeting same
AssigneeThe Trustees of the University of Pennsylvania
InventorsJerome F. Strauss, Mary D. Sammel, Rita Leite, Amy Brown
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Abstract
The present invention provides methods of predicting or detecting labor in a female subject and methods of testing a compound for an ability to delay the onset of labor. The present invention also provides methods of testing a labor marker useful in the diagnostic methods, isolated peptides identified in the present invention, methods for inhibiting labor, utilizing the peptides, and kits comprising methods of the present invention.
Claims5
A method for detecting or diagnosing labor status in a pregnant female subject, the method comprising:
- obtaining a biological sample from said subject;
- testing said sample to detect the amount of the amino acid sequences set forth in SEQ ID NOs:
- 7 and 10 in said sample;
- determining whether the presence of said amino acid sequences is higher than a pre-determined reference level, wherein the presence of said amino acid sequences higher than said pre-determined reference level indicates that said subject is in labor status, thereby detecting or diagnosing labor status in said subject.
1 more element
Dependencies are inferred from the claim text.