Soluble heterodimeric cytokine receptor
AssigneeZymoGenetics, Inc.
InventorsYasmin A. Chandrasekher, Julia E. Novak, Donald C. Foster, Wenfeng Xu, Stephen R. Jaspers
Life of this patent
Estimating the term…
Abstract
The present invention provides methods of treating psoriasis in a subject (i.e., psoriasis associated with a joint disease), by administering to the subject an effective dose of a composition comprising a soluble IL-22R/IL-20RB heterodimeric polypeptide, wherein the heterodimeric polypeptide comprises an IL-22R extracellular domain covalently linked to an IL-20RB extracellular domain.
Claims5
A method of treating psoriasis in a subject, wherein the psoriasis is associated with a joint disease in the subject, the method comprising administering to said subject an effective dose of a composition comprising a soluble IL-22R/IL-20RB heterodimeric polypeptide, wherein said heterodimeric polypeptide comprises an IL-22R extracellular domain covalently linked to an IL-20RB extracellular domain, thereby treating psoriasis.
Dependencies are inferred from the claim text.