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US 8,133,421 B2Granted
Methods of making shaped load-bearing osteoimplant
AssigneeWarsaw Orthopedic, Inc.
InventorsTodd M. Boyce, Lawrence A. Shimp, Albert Manrique, John M. Winterbottom
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Abstract
A load-bearing osteoimplant which comprises a shaped, coherent aggregate of bone particles.
Claims28
A method for making a load-bearing osteoimplant which comprises:
- providing an aggregate containing a population of bone particles and, optionally, one or more optional components selected from the group consisting of binder, filler, plasticizer, wetting agent, surface active agent, biostatic/biocidal agent, bioactive substance, reinforcing material and reinforcing structure,
- wherein at least some of the bone particles in the population are not fully demineralized and at least some of the bone particles in the population are fibrous bone particles;
- and
- shaping the aggregate into a coherent mass in at least one shaping operation to provide a shaped composite having an initial configuration for subsequent shaping into a desired osteoimplant or a final configuration corresponding to that of the osteoimplant, wherein the shaped composite has a bulk density of greater than approximately 0.7 g/cm3.
1 more element
Dependencies are inferred from the claim text.