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US 8,129,118 B2Granted
Magnetic glass particles, method for their preparation and uses thereof
AssigneeRoche Diagnostics GmbH
InventorsKurt Weindel, Michael Riedling, Albert Geiger
Life of this patent
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Abstract
This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them, as well as to suspensions thereof and their uses for the purification of DNA or RNA in particular in automated processes.
Claims17
A procedure for isolating a biological material comprising;
- a) contacting a sample that contains the biological material in a liquid with a composition of magnetic glass particles, wherein each magnetic glass particle comprises at least one magnetic object with a mean diameter between 5 to 500 nm, wherein the glass comprises a metal and metal oxides, wherein the metal is zinc, and the metal oxides are SiO2, B2O3, Al2O3, K2O CaO, and ZnO, under conditions in which the biological material binds non-covalently to the surface of the magnetic glass particle, wherein the binding does not comprise precipitation to lower the solubility of the material to be bound, and
- b) separating the biological material from the liquid.
Dependencies are inferred from the claim text.