ARL-1 specific antibodies
AssigneeBoard of Trustees of Southern Illinois University
InventorDeliang Cao
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Abstract
This invention provides antibodies immunologically specific for human ARL-1 (also referred to AKR1B10), a species of the aldo-keto reductase superfamily of proteins. The invention also provides methods of making and methods of using said antibodies.
Claims72
An isolated antibody or antigen-binding fragment thereof that specifically binds to human ARL-1 protein, wherein the isolated antibody is produced by immunizing an animal using a peptide antigen consisting of the amino acid sequence identified by SEQ ID NO:1, and wherein the antibody is a monoclonal antibody.
An isolated antibody or antigen-binding fragment thereof that specifically binds to an epitope defined by the amino acid sequence as identified by SEQ ID NO:1, wherein the antibody is a monoclonal antibody.
An isolated peptide consisting of the amino acid sequence of SEQ ID NO:1.
Dependencies are inferred from the claim text.