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US 8,097,653 B2Granted
Dosage unit comprising a prostaglandin analog for treating constipation
AssigneeSucampo AG
InventorsRyuji Ueno, Myra L. Patchen
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Abstract
A dosage unit for treating constipation in a human patient is described. The dosage unit of the invention comprises a halogenated prostaglandin analog and a pharmaceutically suitable excipient. The dosage unit relieves constipation without substantial side effects.
Claims7
A method for relieving constipation in a human patient in need of relief of constipation that comprises administering to the patient a dosage unit comprising (i) 24 μg+/−10% of a PG analog represented by Formula (I) and/or its tautomer and (ii) a pharmaceutically suitable excipient:
- where A1 and A2 are fluorine atoms and B is —COOH, including its pharmaceutically acceptable salts, esters or amides, to thereby relieve constipation in the patient,
- wherein said dosage unit is administered enough times per day so that the total daily dose of the PG analog is in the range of about 48-72 μg.
Dependencies are inferred from the claim text.