Method of diagnosis
AssigneeSouthern Medical Diagnostics Pty Ltd
InventorsIan Ross Doyle, Andrew David Bersten, Terence Evan Nicholas
Life of this patent
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Abstract
The present invention relates generally to a method of diagnosing or predicting the development of lung damage and more particularly, to a method of diagnosing or predicting the development of alveolo-capillary membrane damage. The method of the present invention is useful inter alia for detecting lung damage or predicting the development of lung damage such as that caused by noxious agents or as an undesirable side effect resulting from exposure to a therapeutic agent and for monitoring the progress of lung damage.
Claims15
A method of diagnosing lung damage in a mammal, said method comprising:
- identifying a mammal who is asymptomatic to lung damage;
- measuring a level of SP-B in a body fluid of the mammal;
- comparing the measured level of SP-B to a normal reference level of SP-B;
- and
- detecting an increase in the measured level of SP-B in the mammal, wherein said increase is indicative of lung damage in the mammal.
A method of diagnosing lung damage in a mammal who has been exposed to a lung injury factor, said method comprising:
- identifying a mammal who has been exposed to a foreign agent, a noxious or toxic agent, or a therapeutic agent;
- measuring a level of SP-B in a body fluid of the mammal;
- comparing the measured level of SP-B to a normal reference level of SP-B;
- and
- detecting an increase in the measured level of SP-B in the mammal, wherein said increase is indicative of lung damage in the mammal,
- wherein the clinical diagnosis of lung damage in the mammal cannot otherwise be confirmed without the aid of one or more invasive procedures.
A method of diagnosing alveolo-capillary membrane damage in a mammal, said method comprising:
- identifying a mammal who is asymptomatic to alveolo-capillary membrane damage;
- measuring a level of SP-B in a body fluid of the mammal;
- comparing the measured level of SP-B to a normal reference level of SP-B;
- and
- detecting an increase in the measured level of SP-B in the mammal, wherein said increase is indicative of alveolo-capillary membrane damage in the mammal.
Dependencies are inferred from the claim text.