US 8,093,380 B2Granted

Compounds with the bicyclo[4.2.1]nonane system for the treatment of Flaviviridae infections

AssigneePharmasset, Inc.

InventorsPeiyuan Wang, Lieven J. Stuyver, Kyoichi A. Watanabe, Abdalla Hassan, Byoung-Kwon Chun, Laurent Hollecker

Life of this patent

Estimating the term…

Abstract

The disclosed invention is a bicyclo[4.2.1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially humans.

Claims1

Dependent claims

A compound of the formula:

or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 10/632,997Filed 1 Aug 2003 · us provisional application
Priority: 1 Aug 2002
Published: US 2004/0082574 A129 Apr 2004
Granted: 10 Jan 2012
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

C07H 19/167
Purine radicals: with ribosyl as the saccharide radical
A61K 31/513
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
A61K 31/553
Having seven-membered rings, e.g. azelastine, pentylenetetrazole: having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine,…
A61K 31/58
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids: containing heterocyclic rings, e.g. danazol,…

Family

Application60/453,716Us provisional application · filed 1 Aug 2002
US 2004/0082574 A1Pre-grant publication · published 29 Apr 2004
US 8,093,380 B2This patent

From the US filing history. Foreign family members aren’t listed.

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