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AssigneeGenomatica, Inc.
InventorsAnthony P. Burgard, Priti Pharkya, Robin E. Osterhout
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The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective adipate, 6-aminocaproic acid or caprolactam pathway. The invention additionally provides a method for producing adipate, 6-aminocaproic acid or caprolactam. The method can include culturing an adipate, 6-aminocaproic acid or caprolactam producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an adipate, 6-aminocaproic acid or caprolactam pathway enzyme in a sufficient amount to produce the respective product, under conditions and for a sufficient period of time to produce adipate, 6-aminocaproic acid or caprolactam.
A host microbial organism in which exogenous nucleic acids are introduced, wherein said exogenous nucleic acids encode adipate pathway enzymes expressed in a sufficient amount to produce adipate, said adipate pathway comprising a succinyl-CoA:acetyl-CoA acyl transferase;
Dependencies are inferred from the claim text.