2-amino-bicyclo(3.1.0) hexane-2,6-dicarboxylic ester derivative
AssigneeTaisho Pharmaceuticals Co., Ltd.
InventorsAkito Yasuhara, Kazunari Sakagami, Hiroshi Ohta, Atsuro Nakazato
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AssigneeTaisho Pharmaceuticals Co., Ltd.
InventorsAkito Yasuhara, Kazunari Sakagami, Hiroshi Ohta, Atsuro Nakazato
Estimating the term…
A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administration A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative represented by formula [I] [wherein R1 and R2 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; X represents a hydrogen atom or a fluorine atom; Y represents —OCHR3R4 or the like (wherein R3 and R4 are identical or different, and each represents a hydrogen atom, a C1-10alkyl group or the like; and n represents integer 1 or 2)], a pharmaceutically acceptable salt thereof or a hydrate thereof.
A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester compound, or a pharmaceutically acceptable salt thereof, represented by formula [I]
A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester compound, or a pharmaceutically acceptable salt thereof, represented by formula [II]
Dependencies are inferred from the claim text.