US 8,076,450 B2Granted

Treatment of ischemia

AssigneeMorehouse School of Medicine

InventorsRoger P. Simon, Zhi-Gang Xiong

Life of this patent

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A system, including methods and compositions, for treatment of ischemia.

Dependent claims

A method of treating ischemia, comprising:

administering a therapeutically effective amount of an acid sensing ion channel 1a (ASIC1a) inhibitor to an ischemic subject to reduce injury resulting from ischemia, wherein the ASIC1a inhibitor comprises PcTx1.

Dependencies are inferred from the claim text.

C07K 14/43518
From arachnidae: from spiders
A61K 31/439
Having six-membered rings with one nitrogen as the only ring hetero atom: the ring forming part of a bridged ring system, e.g. quinuclidine
A61K 31/4418
Non condensed pyridines; Hydrogenated derivatives thereof: having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
A61K 31/4965
Having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines: non-condensed pyrazines

From the US filing history. Foreign family members aren’t listed.

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