Renin inhibitors

A compound of formula I,

• or a pharmaceutically acceptable salt thereof, or an optical isomer thereof, wherein
• X is N or CH;
• Y is O, CH2, or a bond;
• R1 is
• —(CH2)1-3OR4, or
• —O(CH2)1-2OR4;
• R2 is selected from the group consisting of
• —(CH2)1-5OR4,
• —O(CH2)2-4OR4,
• —C(O)R4,
• —OR4,
• —O(CH2)2-4O—(C3-C8cycloalkyl), wherein cycloalkyl is unsubstituted or substituted with C1-C4alkyl or C1-C4alkanol,
• —O(CH2)2-4NR4R5,
• R4 and R5 are independently C1-C6alkyl unsubstituted or substituted with —OH or CF3.