Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors

A compound of formula (I):

• wherein
• represents a single or double bond, such that at least one bond within the 5 membered ring system is a double bond;
• Ring A may be optionally substituted by 1,2 or 3 Ra groups;
• R4 and R5 independently represent hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, C1-6 alkanol, haloC1-6 alkyl, —(CH2)n—NRxRy, —(CH2)s—COORz, —(CH2)n—O—(CH2)m—OH, —(CH2)n-aryl, —(CH2)n—O-aryl, —(CH2)n-heterocyclyl or —(CH2)n—O-heterocyclyl wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, aryl and heterocyclyl groups may be optionally substituted by 1, 2 or 3 Ra groups;
• Rx, Ry and Rz independently represent hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkanol, —COOC1-6 alkyl, hydroxy, C1-6 alkoxy, haloC1-6 alkyl, —CO—(CH2)n—C1-6 alkoxy, C1-6 alkylamino, C3-8 cycloalkyl or C3-8 cycloalkenyl;
• R2 represents a —CONR7R8 or —CORx group;
• R7 and R8 independently represent hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, aryl, heterocyclyl or R7 and R8 together with the nitrogen atom to which they are attached may form a nitrogen containing heterocyclyl ring, wherein said C1-6 alkyl, aryl and heterocyclyl may be optionally substituted by 1, 2 or 3 Rb groups;
• Ra represents halogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, —ORx, —O—(CH2)n—ORx, haloC1-6 alkyl, haloC1-6 alkoxy, C1-6 alkanol, ═O, ═S, nitro, Si(Rx)4, —(CH2)s—CN, —S—Rx, —SO—Rx, —SO2—Rx, —CORx, —(CRxRy)s—COORz, —(CH2)s—, CONRxRy, —(CH2)s—NRxRy, —(CH2)s—NRxCORy, —(CH2)s—NRxSO2—Ry, —(CH2)s—NH—SO2—NRxRy, —OCONRxRy, —(CH2)s—NRxCO2Ry, —O—(CH2)s—CRxRy—(CH2)t—ORz or —(CH2)s—SO2NRxRy groups;
• Rb represents an Ra group or a —Y-carbocyclic or —Z-heterocyclyl group wherein said carbocyclic and heterocyclyl groups may be optionally substituted by 1, 2 or 3 Ra groups;
• Y and Z independently represent a bond, —CO—(CH2)s—, —COO—, —(CH2)n—, —NRx—(CH2)s—, —(CH2)s—NRx—, —CONRx—, —NRxCO—, —SO2NRx—, —NRxSO2—, —NRxCONRy—, —NRxCSNRy—, —O—(CH2)s—, —(CH2)s—O—, —S—, —SO— or —(CH2)s—SO2—;
• m and n independently represent an integer from 1-4;
• s and t independently represent an integer from 0-4;
• or a pharmaceutically acceptable salt thereof.