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US 8,076,350 B2Granted
Spirocyclic azaadamantane derivatives and methods of use
AssigneeAbbott Laboratories
InventorsJianguo Ji, Michael R. Schrimpf, Kevin B. Sippy, Tao Li, Chih-Hung Lee
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Abstract
The invention relates to compounds that are spirocyclic azaadamantane derivatives derivatives, particularly spirocyclic azaadamantanyl ether or amine derivatives, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.
Claims6
A compound of formula (I)
- or a pharmaceutically acceptable salt or prodrug thereof, wherein
- A is N;
- X1 is CRx1;
- X2 is CRx2;
- X3 is CRx3;
- X4 is CRx4;
- L1 is —O—;
- L2 is —CH2—;
- and
- Rx1, Rx2, Rx3, and Rx4 are each independently H, alkyl, aryl, halogen, or heteroaryl.
7 more elements
Dependencies are inferred from the claim text.