N- (2-aminophenyl) benzamide derivative having urea structure

A compound represented by the following formula (1) or pharmaceutically acceptable salt thereof:

• wherein R1 and R2 are the same or different and represent a hydrogen atom, a lower alkyl group which may have a substituent, or a group represented by the following formula (2);
• R3 represents a hydroxy group, a lower alkoxy group which may have a substituent, a lower cycloalkyloxy group which may have a substituent, an aryloxy group which may have a substituent, —NRaRb, or a group represented by the following formula (3);
• R4 and R5 are the same or different and represent a halogen atom, a lower alkyl group which may have a substituent, a hydroxy group, or a lower alkoxy group which may have a substituent;
• R6 represents a halogen atom, a lower alkyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, an aryl group which may have a substituent, a heterocyclic group which may have a substituent, a hydroxy group, a lower alkoxy group which may have a substituent, a lower cycloalkyloxy group which may have a substituent, an aryloxy group which may have a substituent, a formyl group, a lower alkylcarbonyl group which may have a substituent, a carboxy group, a lower alkoxycarbonyl group which may have a substituent, a nitro group, a cyano group, —NRcRd, or —NRe(CORf);
• R7 represents a lower alkyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, an aryl group which may have a substituent, a hydroxy group, a lower alkoxy group which may have a substituent, a lower cycloalkyloxy group which may have a substituent, or an aryloxy group which may have a substituent;
• Ra, Rb, Rc, Rd, Re, and Rf are the same or different and represent a hydrogen atom, a lower alkyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, or an aryl group which may have a substituent;
• the ring A represents a hydrocarbon ring or a heterocyclic ring;
• the ring B represents a heterocyclic ring having one or plural heteroatoms selected from the group consisting of a nitrogen atom, an oxygen atom, and a sulfur atom in the ring;
• X represents a lower alkylene group which may have a substituent;
• Y and Z are the same or different and represent a single bond or a lower alkylene group which may have a substituent;
• and
• l, m, n, and o are the same or different and represent 0, 1, 2, or 3, in the case where l, m, n, and o represent 2 or 3, the respective groups represented by R4, R5, R6, or R7 may be the same or different.