Pyrimidine nucleoside derivatives and salts thereof
AssigneeaRigen Pharmaceuticals, Inc.
InventorsHaruhiko Machida, Masaichi Yamamoto
Life of this patent
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Abstract
A novel pyrimidine nucleoside derivative represented by the following formula (1) and a salt thereof, as well as a pharmaceutical composition comprising the same as an active ingredient have excellent antiviral properties and are useful as antiviral therapeutic agents: [wherein R represents a nitrogen-containing heterocyclic ring which may have any one of a C1-C3 alkyl group or a C1-C3 alkoxy group as a substituent, or a C1-C6 alkyl group which has one primary amino group as a substituent].
Claims13
A pyrimidine nucleoside represented by the following formula (I) or a salt thereof:
- wherein R represents a nitrogen-containing heterocyclic ring which may have any one of a C1-C3 alkyl group or a C1-C3 alkoxy group as a substituent, or a C1-C6 alkyl group which has one primary amino group as a substituent.
A method for treating a herpes virus infection selected from HSV-1 and VZV, which comprises administering a therapeutically effective amount of at least one pyrimidine nucleoside represented by the following formula (1) or salt thereof to a patient in need of treatment:
- wherein R represents a nitrogen-containing heterocyclic ring which may have any one of a C1-C3 alkyl group or a C1-C3 alkoxy group as a substituent, or a C1-C6 alkyl group which has one primary amino group as a substituent.
Dependencies are inferred from the claim text.