Treatment for obesity
AssigneeUnigene Laboratories Inc.
InventorsNozer M. Mehta, Amy Sturmer, William Stern, James P. Gilligan
Life of this patent
Estimating the term…
Abstract
The present invention provides peptides and pharmaceutical compositions thereof for appetite suppression and weight control. Preferred peptides are calcitonin analogs, preferably with specific amino acid changes to make the peptide more amylin-like.
Claims30
A peptide having the amino acid sequence set forth in SEQ ID NO:1 wherein:
- (i) residue 26 may be either asparagine or aspartic acid,
- (ii) residue 29 may be either serine or alanine, and
- (iii) residue 30 is asparagine or residue 32 is tyrosine.
A peptide having the amino acid sequence set forth in SEQ ID NO:3.
A peptide having the amino acid sequence set forth in SEQ ID NO:4.
A peptide having the amino acid sequence set forth in SEQ ID NO:2 wherein:
- (i) residue 25 may be either asparagine or aspartic acid,
- (ii) residue 28 may be either serine or alanine, and
- (iii) residue 29 is aparagine or residue 31 is tyrosine.
A peptide having the amino acid sequence set forth in SEQ ID NO:5.
A peptide having the amino acid sequence set forth in SEQ ID NO:6.
A peptide having the amino acid sequence set forth in SEQ ID NO:7.
A peptide having the amino acid sequence set forth in SEQ ID NO:8.
A peptide having the amino acid sequence set forth in SEQ ID NO:12.
A peptide having the amino acid sequence set forth in SEQ ID NO:13.
A peptide having the amino acid sequence set forth in SEQ ID NO:14.
Dependencies are inferred from the claim text.