Antimicrobial peptides and use thereof
AssigneeDermagen AB
InventorsArtur Schmidtchen, Martin Malmsten, Björn Walse
Life of this patent
Estimating the term…
Abstract
The invention relates to a molecule comprising at least the amino acid sequence X1 X2 X3 X4 X5 X6 W X8 X9 X10 wherein X4,6,9 is any amino acid residue, X1 is I, L or V, X2 is not C, X3 is A, E, Q, R or Y, X5 is not R, X8 is I or L, X10 is not H and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof. The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the invention to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.
Claims20
A molecule comprising at least the amino acid sequence X1-X2-X3-X4X5-X6-X7-X8-X9-X10, wherein
- X1 is V, L or I;
- X2 is F, K or T;
- X3 is R;
- X4 is L;
- X5 is K;
- X6 is K;
- X7 is W;
- X8 is I or L;
- X9 is Q, R or K;
- and
- X10 is K;
- wherein said molecule has a length of from 10 to 35 amino acid residues, and wherein said amino acid sequence is not SEQ ID NO:2.
A molecule comprising a sequence selected from the group consisting of SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9 and SEQ ID NO:10,
- wherein the molecule has a length of from up to 35 amino acid residues.
Dependencies are inferred from the claim text.