Back to results
US 8,076,107 B2Granted
Production of monatin stereoisomers
AssigneeCargill, Incorporated
InventorsSubash Buddoo, Amanda Louise Rousseau, Dean Brady, James Lalonde, Yiming Yao, Yifong Wang
Life of this patent
Estimating the term…
Abstract
Methods and materials for the production of the high intensity sweetener, monatin, in stereoisomerically-pure or stereoisomerically-enriched form are disclosed. For example, methods using stereoisoselective hydrolysis and separation of a monatin-derived lactone ester are disclosed.
Claims8
A process, comprising:
- (a) reacting a monatin composition comprising S,S and R,R stereoisomeric forms of monatin under conditions suitable for producing ester derivatives of the S,S and R,R stereoisomeric forms of monatin;
- (b) stereospecifically hydrolyzing one of either the S,S ester derivative or R,R ester derivative to form an acid derivative;
- and,
- (c) separating the ester derivative from the acid derivative, wherein reacting the monatin includes:
- initially forming a diester derivative and a lactone ester derivative of the S,S and R,R stereoisomeric forms of monatin;
- and
- converting the initially formed diester derivative to the lactone ester derivative of the S,S and R,R stereoisomeric forms of monatin under suitable reaction conditions.
4 more elements
Dependencies are inferred from the claim text.