Autodestructive transdermal therapeutic system
AssigneeLTS Lohmann Therapie-Systeme AG
InventorsHans-Rainer Hoffmann, Thomas Hille
Life of this patent
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Abstract
The invention relates to a transdermal therapeutic system (TTS), preferably in the form of a transdermal plaster, that contains an active substance and an agent which can destroy the active substance. The TTS further includes a means of bringing the active substance, e.g. buprenorphine, and the agent, e.g. potassium permanganate, into contact when the TTS is removed from the skin of the patient, thereby causing the active substance to be destroyed.
Claims14
A transdermal therapeutic system (TTS) comprising an active ingredient, an agent which can render the active ingredient inactive, and a star-shaped piercing means by which the active ingredient and the agent are brought into contact with one another when removing the TTS from a patient's skin thereby destroying the active ingredient.
A transdermal therapeutic system comprising an active ingredient, an agent which can render the active ingredient inactive, and a star-shaped piercing means by which the active ingredient and the agent are brought into contact with one another by removing the TTS from a patient's skin thereby destroying the active ingredient, wherein
- said active ingredient is contained within a polymer layer disposed upon a siliconized film;
- an absorbent material is disposed upon the active-ingredient-containing-polymer-layer on a side opposing the siliconized film;
- a rigid star-shaped piercing means by which the active ingredient and the agent are brought into contact with one another during removal of the TTS is disposed upon the absorbent material,
- a bag filled with a solution containing the agent which can render the active ingredient inactive is disposed upon the means by which the active ingredient and the agent are brought into contact with one another and pierced thereby during removal of the TTS;
- an active-ingredient-free adhesive layer is disposed on the bag that projects all round beyond the active-ingredient-containing-polymer layer and
- a film is disposed on the active-ingredient-free adhesive layer.
Dependencies are inferred from the claim text.