Polymethylmethacrylate revision bone cement
AssigneeHeraeus Kulzer GmbH
InventorsKlaus-Dieter Kühn, Sebastian Vogt, Hubert Büchner
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Abstract
The invention relates to a PMMA revision bone cement having powder and liquid component, in which the powder component contains two or more granular antibiotics whose grain size distribution is equal in that the main screening fraction each of the individual antibiotics is in the same grain size range, in particular in the range of 100-250 μm or 150-250 μm.
Claims9
A polymethylmethacrylate (PMMA) revision bone cement having powder and liquid components, wherein the powder component comprises two or more granular individual antibiotics whose grain size distribution is equal in that a main screening fraction of each of the individual antibiotics is in the same grain size range, wherein the main screening fraction of the antibiotics each comprises at least 50 weight percent of each antibiotic, and wherein the grain size range of the main screening fraction of the individual antibiotics is 100 to 250 gm.
A polymethylmethacrylate (PMMA) revision bone cement having powder and liquid components, wherein the powder component comprises granules of a first antibiotic and granules of a second antibiotic, wherein the granules of said first antibiotic are present in said powder component in a plurality of grain size fractions, and the granules of said second antibiotic are also present in said powder component in a plurality of grain size fractions;
- wherein one of said grain size fractions of said first antibiotic is designated as a main screening fraction of said first antibiotic, and one of said grain size fractions of said second antibiotic is designated as a main screening fraction of said second antibiotic;
- wherein the main screening fraction of said first antibiotic is present in an amount of at least 50 percent by weight based on a total weight of the first antibiotic in the powder component, and the main screening fraction of said second antibiotic is also present in an amount of at least 50 percent by weight based on a total weight of the second antibiotic in the powder component;
- and wherein the grain size of the main screening fraction of said first antibiotic is 100 to 250 μm, and the grain size of the main screening fraction of said second antibiotic is also 100 to 250 μm.
Dependencies are inferred from the claim text.