Diagnosis and treatment of cancer related to human dormancy
OwnerMichael Powellinventor
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Abstract
New devices and methods for diagnosis and compositions and methods for treatment of cancers use combinations of antimicrobial agents and agents that can reverse dormancy and hibernation pathways. We unexpectedly found that surprisingly low doses of anti-hibernation compounds can substantially inhibit cancer cell growth in vitro and can successfully treat cancers, including metastatic cancer. We also unexpectedly found that antimicrobial agents and anti-HDS compounds together can increase the degree of inhibition of cancer cell growth in a synergistic fashion. We conclude that combination therapy with antimicrobial agents and anti-HDS compounds can be effective in treating human patients with cancer.
Claims11
A method for treating cancer in a patient, comprising the steps of:
- (a) identifying a patient susceptible to therapy, said patient diagnosed with:
- (i) breast or pancreatic cancer;
- and
- (ii) human dormancy syndrome (HDS) wherein the diagnosis of the HDS includes a finding of a serum ratio of reverse triiodothyronine to free triiodothyronine (rT3/fT3) of greater than about 4;
- (b) administering at least one first antimicrobial agent;
- and
- (c) administering luteolin, curcumin, niacinamide and ascorbic acid.
Dependencies are inferred from the claim text.