Peptides of the A-chain of proinsulin or insulin
AssigneeThe Walter and Eliza Hall Institute of Medical Research
InventorsStuart Ian Mannering, Leonard Charles Harrison, Anthony Wayne Purcell, Nicholas A. Williamson
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Abstract
The present invention relates generally to the field of immunotherapy and immunodiagnosis of autoimmune conditions. More particularly, the present invention provides peptides of the A-chain of proinsulin or insulin, which are recognized by or are specific for proinsulin- or insulin-sensitized T-cells. The present invention further contemplates the use of the these agents in therapeutic and diagnostic applications for Type 1 diabetes.
Claims6
An isolated peptide consisting of a complete amino acid sequence selected from the group consisting of SEQ ID NO:
- 23, SEQ ID NO:
- 26, SEQ ID NO:
- 27 and SEQ ID NO:
- 35.
Dependencies are inferred from the claim text.