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US 8,075,883 B2Granted
Use of adsorbent carbon microspheres for the treatment of irritable bowel syndrome
AssigneeOcera Therapeutics, Inc.
InventorsAkiko Shibata, Laurent Fischer
Life of this patent
Estimating the term…
Abstract
Adsorbent carbon microspheres are administered to treat irritable bowel syndrome or symptoms associated with irritable bowel syndrome.
Claims12
A method of treating one or more symptoms of irritable bowel syndrome, comprising:
- identifying a subject suffering from irritable bowel syndrome;
- and
- administering to the subject adsorbent carbon microspheres having a particle size of about 0.05 to about 0.8 mm, wherein the adsorbent carbon microspheres have a specific surface area of about 700 m2/g to about 2500 m2/g, have a total amount of acidic groups from about 0.30 to about 1.20 meq/g, and have a total amount of basic groups from about 0.20 to about 1.00 meq/g, and wherein the volume of pores in the adsorbent carbon microspheres having a pore diameter of about 20 to about 15,000 nm is from about 0.04 mL/g to about 0.10 mL/g.
A method of treating irritable bowel syndrome, comprising:
- identifying a subject suffering from abdominal discomfort or pain associated with irritable bowel syndrome;
- and
- administering to the subject an amount of adsorbent carbon microspheres having a particle size of about 0.05 to about 0.8 mm sufficient to reduce the abdominal discomfort or pain, wherein the adsorbent carbon microspheres have a specific surface area of about 700 m2/g to about 2500 m2/g, have a total amount of acidic groups from about 0.30 to about 1.20 meq/g, and have a total amount of basic groups from about 0.20 to about 1.00 meq/g, and wherein the volume of pores in the adsorbent carbon microspheres having a pore diameter of about 20 to about 15,000 nm is from about 0.04 mL/g to about 0.10 mL/g.
A method of treating irritable bowel syndrome, comprising:
- identifying a subject suffering from abdominal distention, increased belching, or flatulence associated with irritable bowel syndrome;
- and
- administering to the subject an amount of adsorbent carbon microspheres having a particle size of about 0.05 to about 0.8 mm sufficient to reduce gas in the subject, wherein the adsorbent carbon microspheres have a specific surface area of about 700 m2/g to about 2500 m2/g, have a total amount of acidic groups from about 0.30 to about 1.20 meq/g, and have a total amount of basic groups from about 0.20 to about 1.00 meq/g, and wherein the volume of pores in the adsorbent carbon microspheres having a pore diameter of about 20 to about 15,000 nm is from about 0.04 mL/g to about 0.10 mL/g.
Dependencies are inferred from the claim text.