Broad spectrum immune and antiviral gene modulation by oral interferon
AssigneeHEMISPHERx BIOPHARMA
InventorsWilliam A. Carter, David Strayer
Life of this patent
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Abstract
An antiviral/immunomodulatory response in an animal is induced by oral administration to an infected animal, including humans, of a human α-interferon. Methods of conferring resistance or mitigating the effects of exposure to a virus including avian influenza are described.
Claims19
A method of mitigating the effects of or conferring resistance to a susceptible viral infection, wherein said viral infection is any pathogen that replicates by a mechanism similar to human or avian influenza virus, comprising, prior to exposure to a virus or shortly after exposure to the virus, but prior to the development of symptoms, orally or nasally administering to an animal α-interferon in an amount of at least 6.6 IU per pound of the animal's body weight so that the effects of the viral infection are mitigated or the resistance is conferred.
A method of conferring resistance to or mitigating the effects of an infectious, avian influenza virus;
- the method comprising:
- prior to exposure to the virus or shortly after exposure to the virus, respectively, and prior to development of symptoms from infection by the virus, orally or nasally administering multiple, glycosylated α-interferon species to a human patient in an amount of at least 6.6 IU per pound of the patient's body weight so that the resistance is conferred or the effects are mitigated.
Dependencies are inferred from the claim text.