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US 8,074,906 B2Granted
Process for milling and preparing powders and compositions produced thereby
AssigneeNanotherapeutics, Inc.
InventorJames D. Talton
Life of this patent
Estimating the term…
Abstract
A method of milling a powder comprising introducing a gas stream containing a cryogenic liquid and a drug carrier gas into a jet mill, and milling a powder with the jet mill in one or more milling passes. A product produced by the method. A milling apparatus comprising a cryogenic gas input system, a powder feeder, a main jet-mill, and at least one output port for collecting the powder.
Claims18
A method of milling a powder, comprising:
- introducing a powder to be milled into a jet mill impact chamber,
- introducing a cold stream comprising a mixture of cryogenic liquid and a carrier gas into the jet mill impact chamber;
- and
- milling the powder in the impact chamber of said jet mill in one or more milling passes.
1 more element
A method of milling a powder, comprising:
- introducing a powder to be milled comprising particles having a diameter ranging from about 100 nanometers to about 1 millimeter into a jet mill impact chamber;
- introducing a cold stream comprising a mixture of liquid nitrogen and a nitrogen gas into the jet mill impact chamber;
- and
- milling the powder in said jet mill impact chamber in two or more milling passes.
1 more element
A milling apparatus, comprising:
- a cryogenic gas input system;
- a powder feeder;
- a main jet-mill comprising an impact chamber;
- and
- at least one output port from said jet-mill for collecting said powder;
- wherein said cryogenic gas input system comprises a cryogenic liquid input and a carrier gas input, wherein said cryogenic liquid input and said carrier gas input are in communication to provide a mixture of cryogenic liquid and a carrier gas prior to the introduction of said mixture into said main jet mill impact chamber.
3 more elements
Dependencies are inferred from the claim text.