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US 8,074,661 B2Granted
Method and apparatus for laser tissue ablation
AssigneeDuke University
InventorsMichael Shane Hutson, Glenn S. Edwards
Life of this patent
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Abstract
A method and apparatus for ablating material. The material is preferably a heterogenous or composite material, such as animal tissue. A table top laser system can be employed in the invention. Alternatively, a larger laser, such as a free electron laser can be employed.
Claims10
A method of ablating a material, the method comprising:
- (a) directing laser radiation at a target material to be ablated, the target material comprising a protein portion and a liquid portion;
- and
- (b) irradiating the target material with:
- i) one or more pulses of laser radiation having a duration ranging from about 1 nanosecond to about 10 microseconds;
- ii) an energy per pulse greater than about 45 microjoules, and
- iii) an average power greater than about 100 mW;
- wherein the duration, energy per pulse, and average power are selected to produce an incident intensity that is less than a threshold amount such that initiating denaturation of the protein portion of the target material occurs before onset of vaporization of the liquid portion of the target material.
4 more elements
Dependencies are inferred from the claim text.