Anti-integrin antibodies, compositions, methods and uses
AssigneeCentocor, Inc.
InventorsJill Giles-Komar, Linda Snyder, Mohit Trikha, Marian T. Nakada
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Abstract
The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Claims21
An isolated human anti-αV subunit antibody or antigen-binding fragment thereof, comprising a human heavy chain having CDR1, CDR2 and CDR3 regions comprising the amino acid sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 respectively, and a human light chain having CDR1, CDR2 and CDR3 regions comprising the amino acid sequences of SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6 respectively.
Dependencies are inferred from the claim text.