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AssigneesDuke University, The Regents of the University of California, University of Alabama at Birmingham Research Foundation
InventorsBarton F. Haynes, Feng Gao, Bette T. Korber, Beatrice H. Hahn, George M. Shaw, Denise Kothe, Ying Ying Li, Julie Decker, Hua-Xin Liao
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The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.
A nucleic acid comprising a codon-optimized nucleotide sequence that encodes the protein encoded by the nucleic acid sequence of FIG. 29C (SEQ ID NO:37).
A nucleic acid comprising the nucleotide sequence set forth in FIG. 29C (SEQ ID NO:37).
Dependencies are inferred from the claim text.