Chaperonin 10 immunosuppression
AssigneeCBio Limited
InventorsGeoffrey R. Hill, Tatjana Banovic, Halle Morton, Alice Christina Cavanagh
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Abstract
The invention is directed to the use of cpn10 in transplantation and particularly to treatment and/or prevention of graft versus host disease. The invention provides a method of administration of cpn10 to a donor and/or recipient animal or cells, tissues or organs derived from the donor, although in a particularly advantageous form treatment of both the donor and recipient animal. The method may further include the administration to the donor and/or recipient animal at least one other immunosuppressive agent to prevent or alleviate graft versus host disease.
Claims6
A method of treating graft versus host disease (GVHD), said method comprising
- administering to a mammalian recipient a pharmaceutically-effective amount of chaperonin 10 (cpn10) comprising the amino acid sequence set forth in FIG. 1 (SEQ ID NO:1).
Dependencies are inferred from the claim text.