Multiplexed photonic membranes and related detection methods for chemical and/or biological sensing applications

A photonic detection system comprising:

• a photonic membrane with through pores, the through pores having inner walls to which chemical or biological target specific anchors are adapted to be attached;
• an optical input to the photonic membrane;
• and
• an optical output detecting arrangement connected with the photonic membrane,
• wherein the through pores are distributed on the photonic membrane along multiple regions of through pores, through pores pertaining to a first region having inner walls to which a first type of chemical or biological target specific anchor is attached, through pores pertaining to a second region having inner walls to which a second type of chemical or biological target specific anchor is attached, and so on,
• wherein the photonic membrane comprises an additional region of through pores to which no chemical or biological target specific anchors are attached, and
• wherein measurement of a detection output of the photonic detection system occurs differentially, by subtraction of a detection output of the additional region of through pores from a detection output of each region of through pores.