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US 8,046,070 B2Granted
Pre-excitation pacing for treatment of hypertension
AssigneeCardiac Pacemakers, Inc.
InventorsRodney W. Salo, Robert Shipley
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Abstract
Described herein are methods and apparatus for treating hypertension with electrical pre-excitation pacing therapy. Electrical pre-excitation of a hypertrophic region advances the timing of the regional contraction and reduces its contribution to the overall contraction. Such pre-excitation pacing therapy may be beneficial to hypertensive patients with an abnormal distribution of ventricular wall stress/strain.
Claims11
An implantable pacing device, comprising:
- pulse generating circuitry for outputting pacing pulses through one or more pre-excitation pacing channels each of which includes an electrode adapted for disposition near a myocardial site;
- a controller programmed to deliver paces through the pre-excitation pacing channel(s) in accordance with a programmed pre-excitation pacing mode when the device is operating in a pre-excitation state;
- a switch operable by the controller for configuring the pre-excitation pacing channel(s) with a pacing electrode selected among a plurality of pacing electrodes;
- a blood pressure sensor communicating with the controller for generating a signal related to a patient's arterial blood pressure, the controller being programmed to derive a blood pressure measurement therefrom;
- wherein the controller is programmed to optimally configure the pre-excitation pacing channel(s) by sequentially reconfiguring the pre-excitation pacing channel(s) with different pacing electrodes and selecting the pacing electrode for use in the pre-excitation pacing channel(s) that results in the greatest decrease in the blood pressure measurement during delivery of pre-excitation pacing.
2 more elements
Dependencies are inferred from the claim text.