System and method for three-dimensional image rendering and analysis
AssigneeCornell Research Foundation, Inc.
InventorsAnthony P. Reeves, William J. Kostis, Claudia Henschke, David Yankelevitz
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Abstract
The present invention relates to methods and systems for conducting three-dimensional image analysis and diagnosis and possible treatment relating thereto. The invention includes methods of handling signals containing information (data) relating to three-dimensional representation of objects scanned by a scanning medium. The invention also includes methods of making and analyzing volumetric measurements and changes in volumetric measurements which can be used for the purpose of diagnosis and treatment.
Claims6
A method of determining volumetric change of size over a period of time comprising:
- a. determining, in a first computer process executed by a processing device, a volumetric doubling time (DT) for a change in volumetric dimension of an object found in a host, the change in volumetric dimension being volumetrically-determined using three-dimensional image information measured from the object by summing voxels in the changed volumetric dimension of the object;
- b. establishing, in a second computer process executed by the processing device, a relationship based on an exponential change model and said period of time between volumetric doubling time and the change in volumetric dimension, the relationship comprising
- DT
- =
- ln
-
-
- 2
- ·
- Δ
-
-
- t
- ln
-
- (
- V
- 2
- /
- V
- 1
- )
- ,
- the period of time being represented by Δt;
- and
- c. determining, in a third computer process executed by the processing device, said change in volumetric dimension over said period of time.
An article of manufacture for determining volumetric change of size over a period of time comprising:
- a machine-readable medium comprising one or more instructions which when executed by a processing device:
- a. determine a volumetric doubling time (DT) for a change in volumetric dimension of an object found in a host, the change in volumetric dimension being volumetrically-determined using three-dimensional image information measured from the object by summing voxels in the changed volumetric dimension of the object;
- b. establish a relationship based on an exponential change model and said period of time between volumetric doubling time and the change in volumetric dimension, the relationship comprising
- DT
- =
- ln
-
-
- 2
- ·
- Δ
-
-
- t
- ln
-
- (
- V
- 2
- /
- V
- 1
- )
- ,
- the period of time being represented by Δt;
- and
- c. determine said change in volumetric dimension over said period of time.
A system for determining volumetric change of size over a period of time comprising:
- a processor configured to:
- a. determine a volumetric doubling time (DT) for a change in volumetric dimension of an object found in a host, the change in volumetric dimension being volumetrically-determined using three-dimensional image information measured from the object by summing voxels in the changed volumetric dimension of the object;
- b. establish a relationship based on an exponential change model and said period of time between volumetric doubling time and the change in volumetric dimension, the relationship comprising
- DT
- =
- ln
-
-
- 2
- ·
- Δ
-
-
- t
- ln
-
- (
- V
- 2
- /
- V
- 1
- )
- ,
- the period of time being represented by Δt;
- and
- c. determine said change in volumetric dimension over said period of time.
Dependencies are inferred from the claim text.