Device and method for wide-field and high resolution imaging of tissue

A device for wide-field and high resolution imaging of a point of interest on an object surface in an object plane, comprising:

• a light source having an illumination plane for illuminating the object surface;
• a narrow-field, high resolution imaging modality defining a first observation line and using the light source;
• a wide-field, low resolution imaging modality arranged in an image plane at a first angle with respect to the object plane, the second imaging modality defining a second observation line and using the light source;
• and
• a lens associated with the second imaging modality, arranged in a lens plane that substantially bisects the first angle,
• the first and second imaging modalities being optically coupled based upon a relative orientation of the first and second observation lines with respect to the illumination plane and the object plane such that the narrow-field, high resolution imaging modality is automatically positioned at the point of interest as found with the wide-field, low resolution imaging modality.