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US 8,044,231 B2Granted
Method for producing dihalo acetoacetic alkyl esters
AssigneeBayer CropScience AG
InventorsSergii Pazenok, Norbert Lui
Life of this patent
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Abstract
The invention relates to a process for preparing alkyl dihaloacetoacetates of the formula (I) by reacting α,α-dihaloamines of the formula (III) with acetic esters of the formula (II) in the presence of bases.
Claims18
A process for preparing an alkyl dihaloacetoacetate of formula (I)
- in which
- X is fluorine, chlorine or CF3,
- X′ is fluorine, chlorine or bromine,
- R1 is selected from H, C1-12-alkyl radicals, C5-18-aryl, Cl, bromine and fluorine and
- R3, independently of R1, is selected from C1-12-alkyl, C5-18-aryl or C7-19-arylalkyl radicals, by reacting α,α-dihaloamines of the formula (III)
- in which
- R4 is selected from C1-12-alkyl radicals, C5-18-aryl radicals or C7-19-arylalkyl radicals,
- R5, independently of R4, is selected from C1-12-alkyl radicals, C5-18-aryl radicals or C7-19-arylalkyl radicals,
- with a carboxylic ester of the formula (II)
- in which
- R2 is selected from H, C1-12-alkyl radicals, C5-18-aryl, Cl, bromine and fluorine.
8 more elements
A process according to claim, wherein the base is at least the selected from the group consisting of alkali metal hydroxides, alkali metal alkoxides, hydrides, alkyllithium reagents and Grignard reagents.
Dependencies are inferred from the claim text.