Back to results
US 8,044,112 B2Granted
Method for applying a coating onto a silicone hydrogel lens
AssigneeNovartis AG
InventorYasuo Matsuzawa
Life of this patent
Estimating the term…
Abstract
The invention provides a cost-effective method for making a silicone hydrogel contact lens having an LbL coating thereon that is not covalently attached to the lens and has good hydrophilicity, intactness and durability. The method comprises LbL coating at high temperature.
Claims20
A method of applying a hydrophilic coating onto a silicone hydrogel contact lens, comprising the steps of:
- (a) prior to contacting with a first coating solution for forming a prime coating which is not covalently attached to the contact lens, rinsing an uncoated contact lens with an organic solvent or a mixture of organic solvents at room temperature;
- (b) contacting the rinsed contact lens with the first coating solution having a temperature of from about 45° C. to about 95° C. to form the prime coating, wherein the first coating solution includes a polyanionic material having a first hydrophobic backbone and multiple ionizable pendant groups, wherein the first coating solution has a pH sufficient low to substantially prevent the ionizable groups from ionizing, wherein the prime coating comprises at least one layer of the polyanionic material;
- (c) rinsing the contact lens coated with the polyanionic material with water at room temperature;
- and
- (d) applying a top coating over the prime coating of the contact lens by contacting said contact lens, which is rinsed in step (c) with water at room temperature, with a second coating solution having a temperature of from about 45° C. to about 95° C. to form the hydrophilic coating on the contact lens, wherein the second coating solution contains a non-charged hydrophilic polymer having a second hydrophobic backbone,
- wherein the formed hydrophilic coating on the contact lens exhibits an increased hydrophilicity and a good durability characterized by surviving a digital rubbing test or 5 autoclave test.
3 more elements
Dependencies are inferred from the claim text.