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US 8,044,100 B2Granted
Methods and compositions for treating amyloid-related diseases
AssigneeBellus Health Inc.
InventorsXianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
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Abstract
Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
Claims11
A compound of the formula (XII):
- wherein:
- Rh is hydrogen or unsubstituted alkyl;
- Ri is unsubstituted C2-C7 alkyl;
- Rj, Rk, Rm, Rn, and Ro are each independently hydrogen or unsubstituted alkyl;
- X+ is hydrogen, a cationic group, or an ester-forming group;
- and
- t1 and t2 are each a single bond or a pharmaceutically acceptable salt, ester, or prodrug thereof.
4 more elements
A compound selected from the group consisting of:
- or a pharmaceutically acceptable salt or ester, thereof.
A pharmaceutical composition comprising a compound selected from the group consisting of:
- and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.