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US 8,044,092 B2Granted
Therapeutic compounds
AssigneeAllergan, Inc.
InventorsYariv Donde, Robert M. Burk, David W. Old
Life of this patent
Estimating the term…
Abstract
A compound having a substituted five or six-membered carbocycle or heterocycle directly bonded to a substituted aryl or heteroaryl ring, wherein said compound has an EC50 value of 20 nM or less at the prostaglandin EP2 receptor according to the cAMP assay. Methods, compositions, and medicaments related thereto are also disclosed.
Claims19
A compound having a formula
- or a pharmaceutically acceptable salt or tautomer thereof;
- wherein the compound has an EC50 value of 20 nM or less in HEK-EBNA cells expressing a PG EP2 receptor subtype according to a cAMP assay.
Dependencies are inferred from the claim text.