Phenyl derivatives and their use as immunomodulators

A compound of the Formula (I),

• wherein the symbol # indicates the two carbon atoms of the phenyl ring bearing R1, R2 and R3 to either of which the group A may be attached;
• and wherein
• A represents
• wherein the asterisks indicate the bond that is linked to the phenyl ring of Formula (I) bearing R1, R2, and R3;
• R1 represents hydrogen, C1-3-alkyl, fluoro, chloro, methoxy, or cyano;
• R2 represents C2-5-alkyl or C1-4-alkoxy;
• R3 represents hydrogen, and if group A is attached to the para-position with respect to R2 of the phenyl ring of the Formula (I) bearing R1, R2, R3, then R3 is a H or methyl;
• R4 represents hydrogen;
• R5 represents methyl, ethyl or methoxy;
• R6 represents —(CH2—(CH2)k—NR61R62, —(CH2)nCH(OH)—CH2—NR61R62, —CH2(CH2)nNHSO2R63, —(CH2)nCH(OH)—CH2—NHSO2R63, —CH2—(CH2)n—NHCOR64, —(CH2)nCH(OH)—CH2—NHCOR64, hydroxy, hydroxy-C2-5-alkoxy, di-(hydroxy-C1-4-alkyl)-C1-4-alkoxy, 2,3-dihydroxypropoxy, 2-hydroxy-3-methoxy-propoxy, —OCH2—(CH2)m—NR61R62, —OCH2—CH(OH)—CH2—NR61R62, —OCH2—(CH2)mNHSO2R63, —OCH2—CH(OH)—CH2—NHSO2R63, —OCH2—(CH2)m—NHCOR64, or —OCH2—CH(OH)—CH2—NHCOR64;
• R61 represents hydrogen, C1-3-alkyl, 2-hydroxyethyl, 2-hydroxy-1-hydroxymethyl-ethyl, 2,3-dihydroxypropyl, carboxymethyl, 1-(C1-5-alkylcarboxy)methyl, 2-carboxyethyl, or 2-(C1-5-alkylcarboxy)ethyl;
• R62 represents hydrogen, methyl, or ethyl;
• R63 represents C1-3-alkyl, methylamino, ethylamino, or dimethylamino;
• R64 represents hydroxymethyl, 2-hydroxyethyl, 2-hydroxy-1-hydroxymethyl-ethyl, or 2,3-dihydroxypropyl;
• k represents the integer 1, 2, or 3;
• m represents the integer 1 or 2;
• n represents 0, 1, or 2;
• and
• R7 represents methyl, ethyl or halogen;
• in free or salt form.